Sivopixant

Antagonist of P2RX3

Structure

SERP Rating

Probe Sivopixant is in the process of SERP review.

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Information

P2RX3

Antagonist

100 nM

Probe Availability:

MedChemExpress

In Vitro Validations

No in Vitro Validations

In Cell Validations

In Vivo Data

Off-Target Selectivity Assesments

Probe Selectivity in Cell:

In cell inhibitory activity IC50 >30000 nM for P2X1, P2X2, P2X4, P2X7 while P2X2/3 had IC50 1100 nM

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SERP ratings and comments

No SERP comments found for Sivopixant